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Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR

Hepatocellular carcinoma (HCC) is one of the most serious and deadly diseases worldwide with limited options for effective treatment. Biomarker-based active compound targeting therapy may shed some light on novel drugs for HCC. The endoplasmic reticulum (ER) stress and unfolded protein response (UPR...

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Detalles Bibliográficos
Autores principales: Ren, Bo, Liu, Hui, Gao, Hang, Liu, Shutong, Zhang, Zehui, Fribley, Andrew M., Callaghan, Michael U., Xu, Zhixiang, Zeng, Qinghua, Li, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696242/
https://www.ncbi.nlm.nih.gov/pubmed/29190976
http://dx.doi.org/10.18632/oncotarget.21750