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PPAR-α acutely inhibits functional activity of ASICs in rat dorsal root ganglion neurons

Peroxisome proliferator-activated receptor-α (PPAR-α), a lipid activated transcription factor of nuclear hormone receptor superfamily, can relieve pain through a rapid-response mechanism. However, little is known about the underlying mechanism. Herein, we report that PPAR-α activation acutely inhibi...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Wang, Jia-Jia, Liu, Ting-Ting, Zhou, Yi-Mei, Qiu, Chun-Yu, Shen, Ding-Wen, Hu, Wang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696243/
https://www.ncbi.nlm.nih.gov/pubmed/29190977
http://dx.doi.org/10.18632/oncotarget.21805