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l-Citrulline Metabolism in Mice Augments CD4(+) T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung

Activation, recruitment, and effector function of T lymphocytes are essential for control of mycobacterial infection. These processes are tightly regulated in T cells by the availability of l-arginine within the microenvironment. In turn, mycobacterial infection dampens T cell responsiveness through...

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Detalles Bibliográficos
Autores principales: Lange, Shannon M., McKell, Melanie C., Schmidt, Stephanie M., Hossfeld, Austin P., Chaturvedi, Vandana, Kinder, Jeremy M., McAlees, Jaclyn W., Lewkowich, Ian P., Way, Sing Sing, Turner, Joanne, Qualls, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696333/
https://www.ncbi.nlm.nih.gov/pubmed/29201027
http://dx.doi.org/10.3389/fimmu.2017.01561