Erythropoietin Attenuates Postoperative Cognitive Dysfunction by Shifting Macrophage Activation toward the M2 Phenotype

Postoperative cognitive dysfunction (POCD) may be driven by transference of the innate immune response to the brain after aseptic surgical damage. Macrophages are key mediators of innate immunity that can display a pro-inflammatory M1 phenotype or an anti-inflammatory M2 phenotype. Erythropoietin (E...

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Detalles Bibliográficos
Autores principales: Lee, Jae Hoon, Kam, Eun Hee, Kim, So Yeon, Cheon, So Yeong, Kim, Eun Jung, Chung, Seungsoo, Jeong, Ji-Hyun, Koo, Bon-Nyeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696349/
https://www.ncbi.nlm.nih.gov/pubmed/29201007
http://dx.doi.org/10.3389/fphar.2017.00839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696349/
https://www.ncbi.nlm.nih.gov/pubmed/29201007
http://dx.doi.org/10.3389/fphar.2017.00839

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