Cargando…

Erythropoietin Attenuates Postoperative Cognitive Dysfunction by Shifting Macrophage Activation toward the M2 Phenotype

Postoperative cognitive dysfunction (POCD) may be driven by transference of the innate immune response to the brain after aseptic surgical damage. Macrophages are key mediators of innate immunity that can display a pro-inflammatory M1 phenotype or an anti-inflammatory M2 phenotype. Erythropoietin (E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jae Hoon, Kam, Eun Hee, Kim, So Yeon, Cheon, So Yeong, Kim, Eun Jung, Chung, Seungsoo, Jeong, Ji-Hyun, Koo, Bon-Nyeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696349/ https://www.ncbi.nlm.nih.gov/pubmed/29201007 http://dx.doi.org/10.3389/fphar.2017.00839

Ejemplares similares

Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction
por: Cheon, So Yeong, et al.
Publicado: (2017)

Scopolamine promotes neuroinflammation and delirium-like neuropsychiatric disorder in mice
por: Cheon, So Yeong, et al.
Publicado: (2021)

Regulation of Microglia and Macrophage Polarization via Apoptosis Signal-Regulating Kinase 1 Silencing after Ischemic/Hypoxic Injury
por: Cheon, So Yeong, et al.
Publicado: (2017)

Intranasal Administration of Interleukin-1 Receptor Antagonist in a Transient Focal Cerebral Ischemia Rat Model
por: Lee, Jae Hoon, et al.
Publicado: (2017)

Inflammasome and Cognitive Symptoms in Human Diseases: Biological Evidence from Experimental Research
por: Cheon, So Yeong, et al.
Publicado: (2020)

Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an in vitro model of ischemic stroke
por: Cheon, So Yeong, et al.
Publicado: (2017)

Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy
por: Cheon, So Yeong, et al.
Publicado: (2023)

Neuroprotective Effect of Dexmedetomidine against Postoperative Cognitive Decline via NLRP3 Inflammasome Signaling Pathway
por: Cho, Inja, et al.
Publicado: (2022)

Blockade of Apoptosis Signal-Regulating Kinase 1 Attenuates Matrix Metalloproteinase 9 Activity in Brain Endothelial Cells and the Subsequent Apoptosis in Neurons after Ischemic Injury
por: Cheon, So Y., et al.
Publicado: (2016)

Cell Type-Specific Mechanisms in the Pathogenesis of Ischemic Stroke: The Role of Apoptosis Signal-Regulating Kinase 1
por: Cheon, So Yeong, et al.
Publicado: (2018)

Inflammatory Response in COVID-19 Patients Resulting from the Interaction of the Inflammasome and SARS-CoV-2
por: Cheon, So Yeong, et al.
Publicado: (2021)

Orthopedic surgery-induced cognitive dysfunction is mediated by CX3CL1/R1 signaling
por: Cho, Inja, et al.
Publicado: (2021)

Bile duct ligation of C57BL/6 mice as a model of hepatic encephalopathy
por: Cho, Inja, et al.
Publicado: (2020)

The Impact of Persistent Noise Exposure under Inflammatory Conditions
por: Cho, Inja, et al.
Publicado: (2023)

Autophagy Enhancers Regulate Cholesterol-Induced Cytokine Secretion and Cytotoxicity in Macrophages
por: Lee, Su Kyoung, et al.
Publicado: (2023)

Low-Dose Dexmedetomidine Reduces Emergence Agitation after Desflurane Anaesthesia in Children Undergoing Strabismus Surgery
por: Kim, Jeongmin, et al.
Publicado: (2014)

Effect of isoflurane post-treatment on tPA-exaggerated brain injury in a rat ischemic stroke model
por: Kim, Eun Jung, et al.
Publicado: (2015)

The Impact of Perioperative Factors on Changes in Diastolic Function after Kidney Transplantation: A Retrospective Analysis
por: Kim, Eun Jung, et al.
Publicado: (2019)

Efficacy of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm: A Randomized, Double-Blind, Controlled Study
por: Kim, Ji Eun, et al.
Publicado: (2016)

Impact of Diabetes Mellitus on Radial and Ulnar Arterial Vasoreactivity after Radial Artery Cannulation: A Randomized Controlled trial
por: Kim, Eun Jung, et al.
Publicado: (2016)

Ability of dynamic preload indices to predict fluid responsiveness in a high femoral-to-radial arterial pressure gradient: a retrospective study
por: Kim, Seon Ju, et al.
Publicado: (2021)

Effect of sarcopenia on postoperative ICU admission and length of stay after hepatic resection for Klatskin tumor
por: Jung, Hyun Eom, et al.
Publicado: (2023)

Accuracy and Efficacy of Impedance Cardiography as a Non-Invasive Cardiac Function Monitor
por: Kim, Go Eun, et al.
Publicado: (2019)

Perioperative respiratory adverse events in children with active upper respiratory tract infection who received general anesthesia through an orotracheal tube and inhalation agents
por: Kim, So Yeon, et al.
Publicado: (2013)

Ramosetron for the prevention of postoperative nausea and vomiting (PONV): a meta-analysis
por: Kim, Won Oak, et al.
Publicado: (2011)

3′-Sialyllactose Protects SW1353 Chondrocytic Cells From Interleukin-1β-Induced Oxidative Stress and Inflammation
por: Baek, Ahreum, et al.
Publicado: (2021)

PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury
por: Song, Juhyun, et al.
Publicado: (2015)

Erythropoietin and Non-Erythropoietic Derivatives in Cognition
por: Newton, Samuel S., et al.
Publicado: (2021)

Dynamics of Erythroferrone Response to Erythropoietin in Rats
por: Xu, Peng, et al.
Publicado: (2022)

Ivermectin and gemcitabine combination treatment induces apoptosis of pancreatic cancer cells via mitochondrial dysfunction
por: Lee, Da Eun, et al.
Publicado: (2022)

Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome
por: Koo, Bon-Nyeo, et al.
Publicado: (2015)

Comparison between use of single lightwand and video laryngoscope-guided lightwand for tracheal intubation in simulated cervical spine-immobilized patients: a single-blind randomized study
por: Kim, Ha Yeon, et al.
Publicado: (2019)

Effect of Equal Ratio Ventilation on Respiratory Mechanics and Oxygenation During Volume-Controlled Ventilation in Pediatric Patients
por: Kim, Ha Yeon, et al.
Publicado: (2021)

Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice
por: Cao, Fei, et al.
Publicado: (2020)

Editorial: Erythropoietin and Its Analogues as Therapeutics for Neurological Diseases
por: Brines, Michael, et al.
Publicado: (2022)

Dynamics of Erythropoietic Biomarkers in Response to Treatment With Erythropoietin in Belgrade Rats
por: Nguyen, Ly M., et al.
Publicado: (2018)

Anti-neuroinflammatory Potential of Natural Products in Attenuation of Alzheimer's Disease
por: Shal, Bushra, et al.
Publicado: (2018)

Analgesic Effect of Intrathecal Morphine Combined with Low-Dose Bupivacaine on Postoperative Analgesia after Liver Resection: A Randomized Controlled Study
por: Ban, MinGi, et al.
Publicado: (2022)

Ginsenoside compound-Mc1 attenuates oxidative stress and apoptosis in cardiomyocytes through an AMP-activated protein kinase–dependent mechanism
por: Hong, So-hyeon, et al.
Publicado: (2020)

Clinical efficacy of the classic laryngeal mask airway in elderly patients: a comparison with young adult patients
por: Kim, Eun Mi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0aog44b3fcp2njvoqnt1v31d1r