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Structural basis for xenobiotic extrusion by eukaryotic MATE transporter

Mulitidrug and toxic compound extrusion (MATE) family transporters export xenobiotics to maintain cellular homeostasis. The human MATE transporters mediate the excretion of xenobiotics and cationic clinical drugs, whereas some plant MATE transporters are responsible for aluminum tolerance and second...

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Detalles Bibliográficos
Autores principales: Miyauchi, Hirotake, Moriyama, Satomi, Kusakizako, Tsukasa, Kumazaki, Kaoru, Nakane, Takanori, Yamashita, Keitaro, Hirata, Kunio, Dohmae, Naoshi, Nishizawa, Tomohiro, Ito, Koichi, Miyaji, Takaaki, Moriyama, Yoshinori, Ishitani, Ryuichiro, Nureki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696359/
https://www.ncbi.nlm.nih.gov/pubmed/29158478
http://dx.doi.org/10.1038/s41467-017-01541-0