Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice

Degradation of maternal proteins by the ubiquitin-proteasome system (UPS) accompanies the maternal-to-zygotic transition. DPPA3/Stella/PGC7, encoded by a maternal effect gene, is present in the nucleus and cytoplasm of zygotes and has been associated with protecting the female pronucleus from TET3-m...

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Detalles Bibliográficos
Autores principales: Shin, Seung-Wook, Vogt, Edgar John, Jimenez-Movilla, Maria, Baibakov, Boris, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696369/
https://www.ncbi.nlm.nih.gov/pubmed/29158485
http://dx.doi.org/10.1038/s41467-017-01387-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696369/
https://www.ncbi.nlm.nih.gov/pubmed/29158485
http://dx.doi.org/10.1038/s41467-017-01387-6

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