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Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice
Degradation of maternal proteins by the ubiquitin-proteasome system (UPS) accompanies the maternal-to-zygotic transition. DPPA3/Stella/PGC7, encoded by a maternal effect gene, is present in the nucleus and cytoplasm of zygotes and has been associated with protecting the female pronucleus from TET3-m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696369/ https://www.ncbi.nlm.nih.gov/pubmed/29158485 http://dx.doi.org/10.1038/s41467-017-01387-6 |