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Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells

Higher-order chromatin organization controls transcriptional programs that govern cell properties and functions. In order for pluripotent stem cells (PSCs) to appropriately respond to differentiation signals, developmental gene loci should be structurally and spatially regulated to be readily availa...

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Detalles Bibliográficos
Autores principales: Ikeda, Hiroki, Sone, Masamitsu, Yamanaka, Shinya, Yamamoto, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696376/
https://www.ncbi.nlm.nih.gov/pubmed/29158493
http://dx.doi.org/10.1038/s41467-017-01679-x