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BL-Hi-C is an efficient and sensitive approach for capturing structural and regulatory chromatin interactions
In human cells, DNA is hierarchically organized and assembled with histones and DNA-binding proteins in three dimensions. Chromatin interactions play important roles in genome architecture and gene regulation, including robustness in the developmental stages and flexibility during the cell cycle. He...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696378/ https://www.ncbi.nlm.nih.gov/pubmed/29158486 http://dx.doi.org/10.1038/s41467-017-01754-3 |