Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones

Optically active spirocyclic compounds play an important role in drug discovery, and new synthetic strategies for the efficient generation of spiro stereocenters are in much demand. Here we report a catalytic enantioselective cycloaddition using spirocyclic donor–acceptor cyclopropanes as a promisin...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Peng-Wei, Liu, Jia-Kuan, Shen, Lan, Cao, Zhong-Yan, Zhao, Xiao-Li, Yan, Jun, Zhou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696380/
https://www.ncbi.nlm.nih.gov/pubmed/29158496
http://dx.doi.org/10.1038/s41467-017-01451-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696380/
https://www.ncbi.nlm.nih.gov/pubmed/29158496
http://dx.doi.org/10.1038/s41467-017-01451-1

Ejemplares similares