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MiR-138 protects cardiac cells against hypoxia through modulation of glucose metabolism by targetting pyruvate dehydrogenase kinase 1

Dysfunction of cardiac cells under hypoxia has been identified as an essential event leading to myocytes functional failure. MiRNAs are importantly regulatory small-noncoding RNAs that negatively regulate gene expression through the direct binding of 3′-UTR region of their target mRNAs. Recent studi...

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Detalles Bibliográficos
Autores principales: Zhu, Hang, Xue, Hao, Jin, Qin-Hua, Guo, Jun, Chen, Yun-Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696451/
https://www.ncbi.nlm.nih.gov/pubmed/28899927
http://dx.doi.org/10.1042/BSR20170296