Health benefits of late-onset metformin treatment every other week in mice

Chronic 1% metformin treatment is nephrotoxic in mice, but this dose may nonetheless confer health benefits if given intermittently rather than continuously. Here, we examined the effects of 1% metformin given every-other week (EOW) or two consecutive weeks per month (2WM) on survival of 2-year-old...

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Detalles Bibliográficos
Autores principales: Alfaras, Irene, Mitchell, Sarah J., Mora, Hector, Lugo, Darisbeth Rosario, Warren, Alessandra, Navas-Enamorado, Ignacio, Hoffmann, Vickie, Hine, Christopher, Mitchell, James R., Le Couteur, David G., Cogger, Victoria C., Bernier, Michel, de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696465/
https://www.ncbi.nlm.nih.gov/pubmed/29167747
http://dx.doi.org/10.1038/s41514-017-0018-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696465/
https://www.ncbi.nlm.nih.gov/pubmed/29167747
http://dx.doi.org/10.1038/s41514-017-0018-7

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