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Krüpple-like-factor 4 Attenuates Lung Fibrosis via Inhibiting Epithelial-mesenchymal Transition

Epithelial-mesenchymal transition (EMT) plays an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Krüpple-like-factor 4 (KLF4), has been suggested to play an important role in the phenotype transition. However, its function in pulmonary fibrosis and EMT of human alveolar ep...

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Detalles Bibliográficos
Autores principales: Lin, Lianjun, Han, Qian, Xiong, Yan, Li, Ting, Liu, Zhonghui, Xu, Huiying, Wu, Yanping, Wang, Nanping, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696468/
https://www.ncbi.nlm.nih.gov/pubmed/29158503
http://dx.doi.org/10.1038/s41598-017-14602-7