Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions

N-Phenyl-2-naphthylamine (P2NA) is an antioxidant used to protect rubbers from flex-cracking. P2NA can be converted in vivo to 2NA, one of the most potent bladder carcinogens. Here, we report the specific and ultra-sensitive quantification of P2NA in the receptor fluid of Franz diffusion cells by ga...

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Detalles Bibliográficos
Autores principales: Marek, Eike Maximilian, Koslitz, Stephan, Weiss, Tobias, Fartasch, Manigé, Schlüter, Gerhard, Käfferlein, Heiko Udo, Brüning, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Toxicokinetics and Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696485/
https://www.ncbi.nlm.nih.gov/pubmed/28900691
http://dx.doi.org/10.1007/s00204-017-2046-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696485/
https://www.ncbi.nlm.nih.gov/pubmed/28900691
http://dx.doi.org/10.1007/s00204-017-2046-2

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