Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids

Microsomal and soluble epoxide hydrolase (mEH and sEH) fulfill apparently distinct roles: Whereas mEH detoxifies xenobiotics, sEH hydrolyzes fatty acid (FA) signaling molecules and is thus implicated in a variety of physiological functions. These epoxy FAs comprise epoxyeicosatrienoic acids (EETs) a...

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Detalles Bibliográficos
Autores principales: Marowsky, Anne, Meyer, Imke, Erismann-Ebner, Kira, Pellegrini, Giovanni, Mule, Nandkishor, Arand, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Toxicokinetics and Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696502/
https://www.ncbi.nlm.nih.gov/pubmed/28975360
http://dx.doi.org/10.1007/s00204-017-2060-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696502/
https://www.ncbi.nlm.nih.gov/pubmed/28975360
http://dx.doi.org/10.1007/s00204-017-2060-4

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