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Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Approximately three quarters of acute hepatitis C (HCV) infections evolve to a chronic state, while one quarter are spontaneously cleared. Genetic predispositions strongly contribute to the development of chronicity. We have conducted a genome-wide association study to identify genomic variants unde...

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Detalles Bibliográficos
Autores principales: Huang, Hailiang, Duggal, Priya, Thio, Chloe L., Latanich, Rachel, Goedert, James J., Mangia, Alessandra, Cox, Andrea L., Kirk, Gregory D., Mehta, Shruti, Aneja, Jasneet, Alric, Laurent, Donfield, Sharyne M., Cramp, Matthew E., Khakoo, Salim I., Tobler, Leslie H., Busch, Michael, Alexander, Graeme J., Rosen, Hugo R., Edlin, Brian R., Segal, Florencia P., Lauer, Georg M., Thomas, David L., Daly, Mark J., Chung, Raymond T., Kim, Arthur Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696522/
https://www.ncbi.nlm.nih.gov/pubmed/29158528
http://dx.doi.org/10.1038/s41598-017-16011-2