Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

The human retrovirus HTLV-1 causes a hematological malignancy or neuroinflammatory disease in ∼10% of infected individuals. HTLV-1 primarily infects CD4(+) T lymphocytes and persists as a provirus integrated in their genome. HTLV-1 appears transcriptionally latent in freshly isolated cells; however,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulkarni, Anurag, Mateus, Manuel, Thinnes, Cyrille C., McCullagh, James S., Schofield, Christopher J., Taylor, Graham P., Bangham, Charles R.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696563/
https://www.ncbi.nlm.nih.gov/pubmed/28965728
http://dx.doi.org/10.1016/j.chembiol.2017.08.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696563/
https://www.ncbi.nlm.nih.gov/pubmed/28965728
http://dx.doi.org/10.1016/j.chembiol.2017.08.016

Ejemplares similares