Cargando…

Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

The human retrovirus HTLV-1 causes a hematological malignancy or neuroinflammatory disease in ∼10% of infected individuals. HTLV-1 primarily infects CD4(+) T lymphocytes and persists as a provirus integrated in their genome. HTLV-1 appears transcriptionally latent in freshly isolated cells; however,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kulkarni, Anurag, Mateus, Manuel, Thinnes, Cyrille C., McCullagh, James S., Schofield, Christopher J., Taylor, Graham P., Bangham, Charles R.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696563/ https://www.ncbi.nlm.nih.gov/pubmed/28965728 http://dx.doi.org/10.1016/j.chembiol.2017.08.016

Ejemplares similares

HTLV-1: Regulating the Balance Between Proviral Latency and Reactivation
por: Kulkarni, Anurag, et al.
Publicado: (2018)

The HTLV-1 Virological Synapse
por: Nejmeddine, Mohamed, et al.
Publicado: (2010)

HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection
por: Bangham, Charles R.M., et al.
Publicado: (2014)

Conference highlights of the 15th international conference on human retrovirology: HTLV and related retroviruses, 4-8 june 2011, Leuven, Gembloux, Belgium
por: Martin, Fabiola, et al.
Publicado: (2011)

The discovery of the first human retrovirus: HTLV-1 and HTLV-2
por: Gallo, Robert C
Publicado: (2005)

Clonality of HTLV-1 differs between infected CD8+ T cells and infected CD4+ T cells in vivo
por: Melamed, Anat, et al.
Publicado: (2014)

Host determinants of HTLV-1 integration site preference
por: McCallin, Amy J, et al.
Publicado: (2015)

Tumor suppressor in lung cancer identifies latency infected cells in non malignant HTLV-1 infection
por: Manivannan, Kiruthika, et al.
Publicado: (2015)

Clonality of HTLV-2 in natural infection
por: Melamed, Anat, et al.
Publicado: (2014)

Is the HTLV-1 Retrovirus Targeted by Host Restriction Factors?
por: Carcone, Auriane, et al.
Publicado: (2022)

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses
por: Simonis, Nicolas, et al.
Publicado: (2012)

CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1
por: Panfil, Amanda R., et al.
Publicado: (2020)

12(th )international conference on human retrovirology: HTLV and related retroviruses
por: Lairmore, Michael D, et al.
Publicado: (2005)

The 15th International Conference on Human Retroviruses: HTLV and Related Viruses
por: Vandamme, Annemie, et al.
Publicado: (2011)

16th International Conference on Human Retrovirology: HTLV and Related Retroviruses
por: Barbeau, Benoit
Publicado: (2014)

HTLV-1 infection: role of CTL efficiency
por: Bangham, Charles R. M.
Publicado: (2008)

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle
por: Aristodemou, Aris E. N., et al.
Publicado: (2023)

The structure and genomic integration site of the HTLV-1 provirus determine selective clonal expansion and transformation to adult T cell leukaemia/lymphoma
por: Cook, Lucy B, et al.
Publicado: (2014)

Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent
por: Miura, Michi, et al.
Publicado: (2018)

Frequency and function of KIR(+) CD8(+) T cells in HTLV-1 infection
por: Twigger, Katie, et al.
Publicado: (2014)

Human T-lymphotropic virus type 1(HTLV-1) integration, HTLV-1-associated infective dermatitis (IDH) and the risk of Adult T cell leukaemia/lymphoma (ATLL)
por: Hlela, Carol, et al.
Publicado: (2011)

Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis
por: Kirk, Paul DW, et al.
Publicado: (2011)

High frequency of CD4(+)FoxP3(+) cells in HTLV-1 infection: inverse correlation with HTLV-1–specific CTL response
por: Toulza, Frederic, et al.
Publicado: (2008)

Nanotechnology based strategies for HIV-1 and HTLV-1 retroviruses gene detection
por: Mozhgani, Sayed-Hamidreza, et al.
Publicado: (2020)

Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling
por: Miura, Michi, et al.
Publicado: (2019)

Estimating rates of de novo infection and mitotic replication in HTLV-1 persistence: de novo infection continues after early infection
por: Laydon, Daniel J, et al.
Publicado: (2015)

HTLV-1 inserts an ectopic CTCF-binding site into the human genome
por: Satou, Yorifumi, et al.
Publicado: (2015)

The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis
por: Melamed, Anat, et al.
Publicado: (2018)

HTLV-1 gene expression by individual infected clones determines susceptibility to lysis by cytotoxic T lymphocytes specific for Tax and HBZ
por: Rowan, Aileen G, et al.
Publicado: (2014)

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma
por: Bangham, Charles R. M.
Publicado: (2023)

Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression
por: Rowan, Aileen G, et al.
Publicado: (2014)

Estimation of clonal diversity in HTLV-1 infection
por: Laydon, Daniel J, et al.
Publicado: (2014)

Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses
por: Doueiri, Rami, et al.
Publicado: (2012)

HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP
por: Niederer, Heather A, et al.
Publicado: (2014)

A proof of concept study of Infliximab for the treatment of HTLV-1-associated myelopathy
por: Martin, Fabiola, et al.
Publicado: (2014)

Three Examples of Chordoma
por: McCullagh, Graham P.
Publicado: (1934)

Clonality, latency and integration of HTLV-1 in vivo
por: Bangham, Charles, et al.
Publicado: (2013)

HTLV-1 Infection and Its Associated Diseases
por: Saito, Mineki, et al.
Publicado: (2012)

Susceptibility of HBZ and Tax expressing primary HTLV-1+ T cell clones to CTL lysis
por: Rowan, Aileen G, et al.
Publicado: (2011)

Phylogeny of HTLV-I isolates from groups with risk antecedents for human retrovirus infections in Argentina
por: Eirin, Maria Emilia, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_gsvnrrvkhu0robfno3bh63cokd