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Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

The human retrovirus HTLV-1 causes a hematological malignancy or neuroinflammatory disease in ∼10% of infected individuals. HTLV-1 primarily infects CD4(+) T lymphocytes and persists as a provirus integrated in their genome. HTLV-1 appears transcriptionally latent in freshly isolated cells; however,...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Anurag, Mateus, Manuel, Thinnes, Cyrille C., McCullagh, James S., Schofield, Christopher J., Taylor, Graham P., Bangham, Charles R.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696563/ https://www.ncbi.nlm.nih.gov/pubmed/28965728 http://dx.doi.org/10.1016/j.chembiol.2017.08.016

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