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Pharmacological inhibition of diacylglycerol acyltransferase-1 and insights into postprandial gut peptide secretion

AIM: To examine the role that enzyme Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT1) plays in postprandial gut peptide secretion and signaling. METHODS: The standard experimental paradigm utilized to evaluate the incretin response was a lipid challenge. Following a lipid challenge, plasma was coll...

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Detalles Bibliográficos
Autores principales: Maciejewski, Benjamin S, Manion, Tara B, Steppan, Claire M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696614/
https://www.ncbi.nlm.nih.gov/pubmed/29184702
http://dx.doi.org/10.4291/wjgp.v8.i4.161