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In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details
Acquired long QT syndrome, mostly as a result of drug block of the Kv11. 1 potassium channel in the heart, is characterized by delayed cardiac myocyte repolarization, prolongation of the T interval on the ECG, syncope and sudden cardiac death due to the polymorphic ventricular arrhythmia Torsade de...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696636/ https://www.ncbi.nlm.nih.gov/pubmed/29201009 http://dx.doi.org/10.3389/fphys.2017.00934 |