Cargando…

In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details

Acquired long QT syndrome, mostly as a result of drug block of the Kv11. 1 potassium channel in the heart, is characterized by delayed cardiac myocyte repolarization, prolongation of the T interval on the ECG, syncope and sudden cardiac death due to the polymorphic ventricular arrhythmia Torsade de...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, William, Windley, Monique J., Vandenberg, Jamie I., Hill, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696636/
https://www.ncbi.nlm.nih.gov/pubmed/29201009
http://dx.doi.org/10.3389/fphys.2017.00934