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Intertwined Precursor Supply during Biosynthesis of the Catecholate–Hydroxamate Siderophores Qinichelins in Streptomyces sp. MBT76

[Image: see text] The explosive increase in genome sequencing and the advances in bioinformatic tools have revolutionized the rationale for natural product discovery from actinomycetes. In particular, this has revealed that actinomycete genomes contain numerous orphan gene clusters that have the pot...

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Detalles Bibliográficos
Autores principales: Gubbens, Jacob, Wu, Changsheng, Zhu, Hua, Filippov, Dmitri V., Florea, Bogdan I., Rigali, Sébastien, Overkleeft, Herman S., van Wezel, Gilles P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696649/
https://www.ncbi.nlm.nih.gov/pubmed/28945067
http://dx.doi.org/10.1021/acschembio.7b00597