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Sequence and Solution Effects on the Prevalence of d-Isomers Produced by Deamidation

[Image: see text] Deamidation of asparagine is a spontaneous and irreversible post-translational modification associated with a growing list of human diseases. While pervasive, deamidation is often overlooked because it represents a relatively minor chemical change. Structural and functional charact...

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Detalles Bibliográficos
Autores principales: Riggs, Dylan L., Gomez, Sonia V., Julian, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696650/
https://www.ncbi.nlm.nih.gov/pubmed/28984444
http://dx.doi.org/10.1021/acschembio.7b00686