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Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts

BACKGROUND: Oral squamous cell carcinoma (OSCC) invades surrounding tissues by upregulating matrix metalloproteinases (MMPs) -2 and −9, which causes over-expression of the Hedgehog signaling proteins Shh and Gli-1 and degradation of the extracellular matrix, thereby creating a “highway” for tumor in...

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Detalles Bibliográficos
Autores principales: Fan, Haixia, Li, Haixia, Liu, Guanyao, Cong, Wei, Zhao, Hong, Cao, Wenwu, Zheng, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696881/
https://www.ncbi.nlm.nih.gov/pubmed/29157266
http://dx.doi.org/10.1186/s13046-017-0633-y