Cargando…

Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection

BACKGROUND: Up to date, Mycobacterium tuberculosis (Mtb) remains as the worst intracellular killer pathogen. To establish infection, inside the granuloma, Mtb reprograms its metabolism to support both growth and survival, keeping a balance between catabolism, anabolism and energy supply. Mtb knockou...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Agudelo, Víctor A., Baena, Andres, Ramirez-Malule, Howard, Ochoa, Silvia, Barrera, Luis F., Ríos-Estepa, Rigoberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697012/
https://www.ncbi.nlm.nih.gov/pubmed/29157227
http://dx.doi.org/10.1186/s12918-017-0496-z