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Fast batch searching for protein homology based on compression and clustering

BACKGROUND: In bioinformatics community, many tasks associate with matching a set of protein query sequences in large sequence datasets. To conduct multiple queries in the database, a common used method is to run BLAST on each original querey or on the concatenated queries. It is inefficient since i...

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Detalles Bibliográficos
Autores principales: Ge, Hongwei, Sun, Liang, Yu, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697088/
https://www.ncbi.nlm.nih.gov/pubmed/29162030
http://dx.doi.org/10.1186/s12859-017-1938-8