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Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice

Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD). Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production. We investigated the role of GA in the progression of renal injury in DN. Albumin (Alb)/creatinine (crea) levels were significant...

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Detalles Bibliográficos
Autores principales: Hou, Shaozhang, Zhang, Ting, Li, Yuan, Guo, Fengying, Jin, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697128/
https://www.ncbi.nlm.nih.gov/pubmed/29238727
http://dx.doi.org/10.1155/2017/2865912