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Transplantation of Rat Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor 2α Improves Blood Perfusion and Arteriogenesis in a Rat Hindlimb Ischemia Model

Mesenchymal stem cells (MSCs) have been increasingly tested in cell-based therapy to treat numerous diseases. Genetic modification to improve MSC behavior may enhance posttransplantation outcome. This study aims to test the potential therapeutic benefits of rat bone marrow MSCs overexpressing hypoxi...

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Detalles Bibliográficos
Autores principales: Lu, Weifeng, Chen, Xiaoli, Si, Yi, Hong, Shichai, Shi, Zhengyu, Fu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697133/
https://www.ncbi.nlm.nih.gov/pubmed/29238372
http://dx.doi.org/10.1155/2017/3794817