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JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B‐Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation

BACKGROUND: Canine diffuse large B‐cell lymphoma (DLBCL) is a common and aggressive hematologic malignancy. The lack of conventional therapies with sustainable efficacy warrants further investigation of novel therapeutics. The Janus kinase (JAK) and signal transducer and activator of transcription (...

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Detalles Bibliográficos
Autores principales: Lu, Z., Hong, C.C., Jark, P.C., Assumpção, A.L.F.V., Bollig, N., Kong, G., Pan, X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697192/
https://www.ncbi.nlm.nih.gov/pubmed/28960447
http://dx.doi.org/10.1111/jvim.14837