TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis

The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions, including steroid hormone biosynthesis, respiration, cell proliferation, and apoptosis. TSPO binds with high affinity to cholesterol and numerous co...

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Detalles Bibliográficos
Autores principales: Owen, David R., Fan, Jinjiang, Campioli, Enrico, Venugopal, Sathvika, Midzak, Andrew, Daly, Edward, Harlay, Aline, Issop, Leeyah, Libri, Vincenzo, Kalogiannopoulou, Dimitra, Oliver, Eduardo, Gallego-Colon, Enrique, Colasanti, Alessandro, Huson, Les, Rabiner, Eugenii A., Suppiah, Puvan, Essagian, Charles, Matthews, Paul M., Papadopoulos, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697202/
https://www.ncbi.nlm.nih.gov/pubmed/29074640
http://dx.doi.org/10.1042/BCJ20170648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697202/
https://www.ncbi.nlm.nih.gov/pubmed/29074640
http://dx.doi.org/10.1042/BCJ20170648

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