Cargando…
TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis
The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions, including steroid hormone biosynthesis, respiration, cell proliferation, and apoptosis. TSPO binds with high affinity to cholesterol and numerous co...
Autores principales: | Owen, David R., Fan, Jinjiang, Campioli, Enrico, Venugopal, Sathvika, Midzak, Andrew, Daly, Edward, Harlay, Aline, Issop, Leeyah, Libri, Vincenzo, Kalogiannopoulou, Dimitra, Oliver, Eduardo, Gallego-Colon, Enrique, Colasanti, Alessandro, Huson, Les, Rabiner, Eugenii A., Suppiah, Puvan, Essagian, Charles, Matthews, Paul M., Papadopoulos, Vassilios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697202/ https://www.ncbi.nlm.nih.gov/pubmed/29074640 http://dx.doi.org/10.1042/BCJ20170648 |
Ejemplares similares
-
Dynamic Remodeling of Membranes and Their Lipids during Acute Hormone-Induced Steroidogenesis in MA-10 Mouse Leydig Tumor Cells
por: Venugopal, Sathvika, et al.
Publicado: (2021) -
Amhr2-Cre–Mediated Global Tspo Knockout
por: Fan, Jinjiang, et al.
Publicado: (2020) -
Identifying improved TSPO PET imaging probes through biomathematics: The impact of multiple TSPO binding sites in vivo
por: Guo, Qi, et al.
Publicado: (2012) -
Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO)()
por: Colasanti, Alessandro, et al.
Publicado: (2013) -
Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells
por: Fan, Jinjiang, et al.
Publicado: (2020)