Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells

Cardiomyocytes hypertrophy and apoptosis induced by advanced glycation end products (AGEs) is the crucial pathological foundation contributing to the onset and development of diabetic cardiomyopathy (DCM). However, the mechanism remains poorly understood. Here, we report that profilin-1 (PFN-1), a w...

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Detalles Bibliográficos
Autores principales: Yang, Dafeng, Wang, Ya, Jiang, Minna, Deng, Xu, Pei, Zhifang, Li, Fei, Xia, Ke, Zhu, Lingyan, Yang, Tianlun, Chen, Meifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697376/
https://www.ncbi.nlm.nih.gov/pubmed/29238726
http://dx.doi.org/10.1155/2017/9716087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697376/
https://www.ncbi.nlm.nih.gov/pubmed/29238726
http://dx.doi.org/10.1155/2017/9716087

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