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Reduced suppressive effect of β(2)-adrenoceptor agonist on fibrocyte function in severe asthma

BACKGROUND: Patients with severe asthma have increased airway remodelling and elevated numbers of circulating fibrocytes with enhanced myofibroblastic differentiation capacity, despite being treated with high doses of corticosteroids, and long acting β(2)-adrenergic receptor (AR) agonists (LABAs). W...

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Detalles Bibliográficos
Autores principales: Lo, Chun-Yu, Michaeloudes, Charalambos, Bhavsar, Pankaj K., Huang, Chien-Da, Chang, Po-Jui, Wang, Chun-Hua, Kuo, Han-Pin, Chung, Kian Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697384/
https://www.ncbi.nlm.nih.gov/pubmed/29162108
http://dx.doi.org/10.1186/s12931-017-0678-7