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Reduced suppressive effect of β(2)-adrenoceptor agonist on fibrocyte function in severe asthma
BACKGROUND: Patients with severe asthma have increased airway remodelling and elevated numbers of circulating fibrocytes with enhanced myofibroblastic differentiation capacity, despite being treated with high doses of corticosteroids, and long acting β(2)-adrenergic receptor (AR) agonists (LABAs). W...
Autores principales: | Lo, Chun-Yu, Michaeloudes, Charalambos, Bhavsar, Pankaj K., Huang, Chien-Da, Chang, Po-Jui, Wang, Chun-Hua, Kuo, Han-Pin, Chung, Kian Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697384/ https://www.ncbi.nlm.nih.gov/pubmed/29162108 http://dx.doi.org/10.1186/s12931-017-0678-7 |
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