Independent impacts of aging on mitochondrial DNA quantity and quality in humans

BACKGROUND: The accumulation of mitochondrial DNA (mtDNA) mutations, and the reduction of mtDNA copy number, both disrupt mitochondrial energetics, and may contribute to aging and age-associated phenotypes. However, there are few genetic and epidemiological studies on the spectra of blood mtDNA hete...

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Detalles Bibliográficos
Autores principales: Zhang, Ruoyu, Wang, Yiqin, Ye, Kaixiong, Picard, Martin, Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697406/
https://www.ncbi.nlm.nih.gov/pubmed/29157198
http://dx.doi.org/10.1186/s12864-017-4287-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697406/
https://www.ncbi.nlm.nih.gov/pubmed/29157198
http://dx.doi.org/10.1186/s12864-017-4287-0

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