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A novel vector for transgenesis in the rat CNS

The larger brain of the rat enables a much greater repertoire of complex behaviors than mice, likely making rats preferential for investigating neurodegeneration. Because molecular tools for specific expression of transgenes in the rat brain are sparse, we chose Prnp encoding the prion protein (PrP)...

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Detalles Bibliográficos
Autores principales: Lopez, T. Peter, Giles, Kurt, Dugger, Brittany N., Oehler, Abby, Condello, Carlo, Krejciova, Zuzana, Castaneda, Julian A., Carlson, George A., Prusiner, Stanley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697436/
https://www.ncbi.nlm.nih.gov/pubmed/29157304
http://dx.doi.org/10.1186/s40478-017-0484-y