Cargando…

A novel vector for transgenesis in the rat CNS

The larger brain of the rat enables a much greater repertoire of complex behaviors than mice, likely making rats preferential for investigating neurodegeneration. Because molecular tools for specific expression of transgenes in the rat brain are sparse, we chose Prnp encoding the prion protein (PrP)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lopez, T. Peter, Giles, Kurt, Dugger, Brittany N., Oehler, Abby, Condello, Carlo, Krejciova, Zuzana, Castaneda, Julian A., Carlson, George A., Prusiner, Stanley B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697436/ https://www.ncbi.nlm.nih.gov/pubmed/29157304 http://dx.doi.org/10.1186/s40478-017-0484-y

Ejemplares similares

Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein
por: Krejciova, Zuzana, et al.
Publicado: (2019)

Insulated piggyBac vectors for insect transgenesis
por: Sarkar, Abhimanyu, et al.
Publicado: (2006)

Bacillus subtilis genome vector-based complete manipulation and reconstruction of genomic DNA for mouse transgenesis
por: Iwata, Tetsuo, et al.
Publicado: (2013)

Transposon-mediated BAC transgenesis in zebrafish and mice
por: Suster, Maximiliano L, et al.
Publicado: (2009)

Evidence That Bank Vole PrP Is a Universal Acceptor for Prions
por: Watts, Joel C., et al.
Publicado: (2014)

Protease-Resistant Prions Selectively Decrease Shadoo Protein
por: Watts, Joel C., et al.
Publicado: (2011)

Refined human artificial chromosome vectors for gene therapy and animal transgenesis
por: Kazuki, Y, et al.
Publicado: (2011)

Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis
por: Chakraborty, Syandan, et al.
Publicado: (2014)

One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT)
por: Ohtsuka, Masato, et al.
Publicado: (2015)

How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer’s Disease and Other Neurodegenerative Disorders
por: Carlson, George A., et al.
Publicado: (2021)

A combination of transposable elements and magnetic cell sorting provides a very efficient transgenesis system for chicken primary erythroid progenitors
por: Mejia-Pous, Camila, et al.
Publicado: (2009)

Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner
por: Xie, Xiayang, et al.
Publicado: (2012)

Transgenesis for pig models
por: Yum, Soo-Young, et al.
Publicado: (2016)

The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates
por: Pavlopoulos, Anastasios, et al.
Publicado: (2007)

Tools for Anopheles gambiae Transgenesis
por: Volohonsky, Gloria, et al.
Publicado: (2015)

Transpositional transgenesis with piggyBac
por: Urschitz, Johann, et al.
Publicado: (2013)

Transgenesis and web resources in quail
por: Serralbo, Olivier, et al.
Publicado: (2020)

A method to preserve low parasitaemia Plasmodium-infected avian blood for host and vector infectivity assays
por: Carlson, Jenny S., et al.
Publicado: (2016)

Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease
por: Condello, Carlo, et al.
Publicado: (2018)

Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus) — towards understanding gene function and regulatory evolution in an ecological model system for rapid phenotypic diversification
por: Kratochwil, Claudius F., et al.
Publicado: (2017)

piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
por: Li, Rongbo, et al.
Publicado: (2013)

A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression
por: Makhija, Harshyaa, et al.
Publicado: (2018)

Remembering Jeff Robbins: The Father of Cardiac Transgenesis
por: Molkentin, Jeffery D., et al.
Publicado: (2022)

Meganuclease and transposon mediated transgenesis in medaka
por: Grabher, Clemens, et al.
Publicado: (2007)

Transient transgenesis of the tapeworm Taenia crassiceps
por: Moguel, Bárbara, et al.
Publicado: (2015)

Establishment of Transgenesis in the Demosponge Suberites domuncula
por: Revilla-i-Domingo, Roger, et al.
Publicado: (2018)

Combining transgenesis with paratransgenesis to fight malaria
por: Huang, Wei, et al.
Publicado: (2022)

Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America
por: Lol, Juan C., et al.
Publicado: (2019)

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS
por: Goodwin, Marshall S., et al.
Publicado: (2020)

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy
por: Woerman, Amanda L., et al.
Publicado: (2020)

Versatile P(acman) BAC Libraries for Transgenesis Studies in Drosophila melanogaster
por: Venken, Koen J. T., et al.
Publicado: (2009)

A strategy to obtain recombinant cell lines with high expression levels. Lentiviral vector-mediated transgenesis
por: Prieto, Claudio, et al.
Publicado: (2011)

Microfluidic devices as model platforms of CNS injury-ischemia to study axonal regeneration by regulating mitochondrial transport and bioenergetic metabolism
por: Huang, Ning, et al.
Publicado: (2022)

Protocol: Streamline cloning of genes into binary vectors in Agrobacterium via the Gateway(® )TOPO vector system
por: Xu, Ruqiang, et al.
Publicado: (2008)

Development of expression vectors based on pepino mosaic virus
por: Sempere, Raquel N, et al.
Publicado: (2011)

A visible dominant marker for insect transgenesis
por: Osanai-Futahashi, Mizuko, et al.
Publicado: (2012)

Antiviral restriction factor transgenesis in the domestic cat
por: Wongsrikeao, Pimprapar, et al.
Publicado: (2011)

Investigating immune responses to parasites using transgenesis
por: Tedla, Mebrahtu G., et al.
Publicado: (2019)

Next-generation plasmids for transgenesis in zebrafish and beyond
por: Kemmler, Cassie L., et al.
Publicado: (2023)

Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy
por: Ayers, Jacob I., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_id28it1q65phd7oc4mf0l56to7