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Active Expression of Human Tissue Plasminogen Activator (t-PA) c-DNA from Pulmonary Metastases in the Methylotrophic Yeast Pichia Pastoris KM71H Strain

BACKGROUND: Human tissue-type plasminogen activator (t-PA) is a key protease of the trypsin family. It catalyzes the activation of zymogen plasminogen to the fibrin-degrading proteinase, plasmin, leading to digestion of fibrin clots. The recombinant enzyme produced by recombinant technology issued t...

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Detalles Bibliográficos
Autores principales: Mohseni, Amir Hossein, Soleimani, Mohammad, Majidzadeh-A, Keivan, Taghinezhad-S, Sedigheh, Keyvani, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697489/
https://www.ncbi.nlm.nih.gov/pubmed/28843264
http://dx.doi.org/10.22034/APJCP.2017.18.8.2249