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1,3‐Bis(aryloxy)propan‐2‐ols as potential antileishmanial agents

We describe herein the synthesis and antileishmanial activity of 1,3‐bis(aryloxy)propan‐2‐ols. Five compounds (2, 3, 13, 17, and 18) exhibited an effective antileishmanial activity against stationary promastigote forms of Leishmania amazonensis (IC (50) < 15.0 μm), and an influence of compound li...

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Detalles Bibliográficos
Autores principales: Lavorato, Stefânia N., Duarte, Mariana C., Lage, Daniela P., Tavares, Carlos A. P., Coelho, Eduardo A. F., Alves, Ricardo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697679/
https://www.ncbi.nlm.nih.gov/pubmed/28590516
http://dx.doi.org/10.1111/cbdd.13024