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Direct arterial injection of hyperpolarized (13)C‐labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution
PURPOSE: A rat model was developed to enable direct administration of hyperpolarized (13)C‐labeled molecules into a tumor‐supplying artery for magnetic resonance spectroscopy (MRS) studies of tumor metabolism. METHODS: Rat P22 sarcomas were implanted into the right inguinal fat pad of BDIX rats such...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697693/ https://www.ncbi.nlm.nih.gov/pubmed/28191664 http://dx.doi.org/10.1002/mrm.26628 |