Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13

The combinatorial expression of Hox genes along the body axes is a major determinant of cell fate and plays a pivotal role in generating the animal body plan. Loss of HOXA13 and HOXD13 transcription factors (HOX13) leads to digit agenesis in mice, but how HOX13 proteins regulate transcriptional outc...

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Detalles Bibliográficos
Autores principales: Sheth, Rushikesh, Barozzi, Iros, Langlais, David, Osterwalder, Marco, Nemec, Stephen, Carlson, Hanqian L., Stadler, H. Scott, Visel, Axel, Drouin, Jacques, Kmita, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697718/
https://www.ncbi.nlm.nih.gov/pubmed/27974206
http://dx.doi.org/10.1016/j.celrep.2016.11.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697718/
https://www.ncbi.nlm.nih.gov/pubmed/27974206
http://dx.doi.org/10.1016/j.celrep.2016.11.039

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