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TGF-β contamination of purified recombinant GDF15

Purified recombinant proteins for use in biomedical research are invaluable to investigate protein function. However, purity varies in protein batches made in mammalian expression systems, such as CHO-cells or HEK293-cells. This study points to caution while investigating effects of proteins related...

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Detalles Bibliográficos
Autores principales: Olsen, Oddrun Elise, Skjærvik, Anette, Størdal, Berit Fladvad, Sundan, Anders, Holien, Toril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697882/
https://www.ncbi.nlm.nih.gov/pubmed/29161287
http://dx.doi.org/10.1371/journal.pone.0187349