Spatiotemporal dynamics of HSV genome nuclear entry and compaction state transitions using bioorthogonal chemistry and super-resolution microscopy

We investigated the spatiotemporal dynamics of HSV genome transport during the initiation of infection using viruses containing bioorthogonal traceable precursors incorporated into their genomes (HSV(EdC)). In vitro assays revealed a structural alteration in the capsid induced upon HSV(EdC) binding...

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Detalles Bibliográficos
Autores principales: Sekine, Eiki, Schmidt, Nora, Gaboriau, David, O’Hare, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697887/
https://www.ncbi.nlm.nih.gov/pubmed/29121649
http://dx.doi.org/10.1371/journal.ppat.1006721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697887/
https://www.ncbi.nlm.nih.gov/pubmed/29121649
http://dx.doi.org/10.1371/journal.ppat.1006721

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