Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak

Cells deficient in the pro-death Bcl-2 family members Bax and Bak are known to be resistant to apoptotic cell death, and previous we have shown that these two effectors are also needed for mitochondrial-dependent cellular necrosis (Karch et al., 2013). Here we show that mouse embryonic fibroblasts d...

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Detalles Bibliográficos
Autores principales: Karch, Jason, Schips, Tobias G, Maliken, Bryan D, Brody, Matthew J, Sargent, Michelle A, Kanisicak, Onur, Molkentin, Jeffery D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697932/
https://www.ncbi.nlm.nih.gov/pubmed/29148970
http://dx.doi.org/10.7554/eLife.30543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697932/
https://www.ncbi.nlm.nih.gov/pubmed/29148970
http://dx.doi.org/10.7554/eLife.30543

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