MicroRNA-146a Mimics Reduce the Peripheral Neuropathy in Type 2 Diabetic Mice

MicroRNA-146a (miR-146a) regulates multiple immune diseases. However, the role of miR-146a in diabetic peripheral neuropathy (DPN) has not been investigated. We found that mice (db/db) with type 2 diabetes exhibited substantial downregulation of miR-146a in sciatic nerve tissue. Systemic administrat...

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Detalles Bibliográficos
Autores principales: Liu, Xian Shuang, Fan, Baoyan, Szalad, Alexandra, Jia, Longfei, Wang, Lei, Wang, Xinli, Pan, Wanlong, Zhang, Li, Zhang, Ruilan, Hu, Jiani, Zhang, Xiao Ming, Chopp, Michael, Zhang, Zheng Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697943/
https://www.ncbi.nlm.nih.gov/pubmed/28899883
http://dx.doi.org/10.2337/db16-1182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697943/
https://www.ncbi.nlm.nih.gov/pubmed/28899883
http://dx.doi.org/10.2337/db16-1182

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