Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract

Urinary tract infections (UTI) are a major problem in human medicine for which better understanding of native immune defenses may reveal new pathways for therapeutic intervention. Tamm-Horsfall glycoprotein (THP), the most abundant urinary protein, interacts with bacteria including uropathogenic E....

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Detalles Bibliográficos
Autores principales: Patras, Kathryn A., Coady, Alison, Olson, Joshua, Ali, Syed Raza, RamachandraRao, Satish P., Kumar, Satish, Varki, Ajit, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698129/
https://www.ncbi.nlm.nih.gov/pubmed/28829050
http://dx.doi.org/10.1038/icb.2017.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698129/
https://www.ncbi.nlm.nih.gov/pubmed/28829050
http://dx.doi.org/10.1038/icb.2017.63

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