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Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract
Urinary tract infections (UTI) are a major problem in human medicine for which better understanding of native immune defenses may reveal new pathways for therapeutic intervention. Tamm-Horsfall glycoprotein (THP), the most abundant urinary protein, interacts with bacteria including uropathogenic E....
Autores principales: | Patras, Kathryn A., Coady, Alison, Olson, Joshua, Ali, Syed Raza, RamachandraRao, Satish P., Kumar, Satish, Varki, Ajit, Nizet, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698129/ https://www.ncbi.nlm.nih.gov/pubmed/28829050 http://dx.doi.org/10.1038/icb.2017.63 |
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