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The structure-energy landscape of NMDA Receptor gating

N-methyl-D-aspartate (NMDA) receptors are the main calcium-permeable excitatory receptors in the mammalian central nervous system. The NMDA receptor gating is complex, exhibiting multiple closed, open, and desensitized states; however, the central questions regarding the conformations and energetics...

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Detalles Bibliográficos
Autores principales: Dolino, Drew M., Chatterjee, Sudeshna, MacLean, David M., Flatebo, Charlotte, Bishop, Logan D.C., Shaikh, Sana A., Landes, Christy F., Jayaraman, Vasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698143/
https://www.ncbi.nlm.nih.gov/pubmed/28991238
http://dx.doi.org/10.1038/nchembio.2487