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Maintenance of PD‐1 on brain‐resident memory CD8 T cells is antigen independent

Infection of the central nervous system (CNS) by murine polyomavirus (MuPyV), a persistent natural mouse pathogen, establishes brain‐resident memory CD8 T cells (bT(RM)) that uniformly and chronically express programmed cell death protein 1 (PD‐1) irrespective of the expression of α(E) integrin CD10...

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Detalles Bibliográficos
Autores principales: Shwetank, Abdelsamed, Hossam A, Frost, Elizabeth L, Schmitz, Heather M, Mockus, Taryn E, Youngblood, Ben A, Lukacher, Aron E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698165/
https://www.ncbi.nlm.nih.gov/pubmed/28829048
http://dx.doi.org/10.1038/icb.2017.62