Dysregulation of the miR-146a-Smad4 axis impairs osteogenesis of bone mesenchymal stem cells under inflammation

Osteoporosis is a common disease that affects patient quality of life, especially among the elderly population. Although inflammation contributes significantly to osteoporosis, the underlying mechanism is unclear. In this study, we found that tumor necrosis factor (TNF)-α, an inflammatory environmen...

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Detalles Bibliográficos
Autores principales: Kuang, Wei, Zheng, Liwei, Xu, Xin, Lin, Yao, Lin, Jiong, Wu, Jiahua, Tan, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698258/
https://www.ncbi.nlm.nih.gov/pubmed/29167750
http://dx.doi.org/10.1038/boneres.2017.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698258/
https://www.ncbi.nlm.nih.gov/pubmed/29167750
http://dx.doi.org/10.1038/boneres.2017.37

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